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  1. Ali M, Bath PMW, Curram J, Davis SM, Diener HC, Donnan GA, Fisher M, Gregson BA, Grotta JC, Hacke W, Hennerici MG, Hommel M, Kaste M, Marler JR, Sacco R, Teal P, Wahlgren NG, Warach S, Weir CJ and Lees KR. The Virtual International Stroke Trials Archive. Stroke 2007;38:1905-1910. 
  2. Ali M, Bath P, Brady M, Davis S, Diener H-C, Donnan G, Fisher M, Hacke W, Hanley DF, Luby M, Tsivgoulis G, Wahlgren N, Warach S,   Lees KR, on behalf of the VISTA Steering Committees, Development, Expansion and Use of a Stroke Clinical Trials Resource for Novel Exploratory Analyses, International Journal of Stroke 2012;7: 133-138.
  3. Diener HC, Weimar C, Ali M, Lees KR, Die virtuelle internationale Schlaganfallstudien-Archiv (VISTA) – Bedeutung für die Schlaganfallforschung, Akt Neurol 2009;36:174-179
  4. Weimar C, Ali M, Lees KR, Donnan GA, Diener HC, for the VISTA Steering Committee. The Virtual International Stroke Trials Archive (VISTA) – Results and impact on future stroke trials and management of stroke patients. International Journal of Stroke 2010; 5: 103-109.

 

Abstracts

 Presentation

 

    1. Ali M, Atula S, Bath PMW, Grotta J, Hacke W, Lyden P, Marler J, Sacco RL, Lees KR, for the VISTA Investigators, Stroke Outcomes in Clinical Trials Patients Deriving from Different Countries. Poster Presented at EFNS, Madrid, Spain, 2008.
    2. Ali M, Lyden P, Sacco RL, Shuaib A, Lees KR, for the VISTA investigators. Natural History of Complications after Intracerebral Haemorrhage. Poster at AAN meeting, Seattle, USA, 2009.
    3. Dawson J, Lees JS, Chang TP, Walters MR, Ali M, Davis SM, Diener HC, Lees KR, for the GAIN and VISTA Investigators. Association between disability measures and healthcare costs after initial treatment for acute stroke. Poster Presented at ISC, San Francisco, USA. 2007.
    4. Dowlatshahi D, Demchuk AM, Flaherty ML, Ali M, Lyden P and Smith EE, and the VISTA Collaborators. A Clinically Relevant Definition for Hematoma Growth Following Intracerebral Hemorrhage. Abstract Presented at ESC, Sweden, 2009.
    5. Dowlatshahi D, Smith EE, Flaherty ML, Ali M, Lyden P and Demchuk AM, and the VISTA Collaborators. Small intracerebral hemorrhages are associated with a low rate of hematoma expansion and do not seem appropriate for ICH hemostatic treatment trials. Abstract Presented at ESC, Sweden, 2009.
    6. Morris JG; Kane K, Fisher M, on behalf of the VISTA Investigators. Pre-treatment with Angiotensin Converting Enzyme Inhibitors (ACEI) or Angiotensin Receptor Blockers (ARB) reduce stroke severity at presentation. Abstract presented at International Stroke Conference San Diego, USA. 2009
    7. Muir KW; McCormick M; Baird T; for the VISTA investigators. Hyperglycaemia in Acute Stroke Trials: Prevalence, Predictors and Prognostic Value- An Analysis of the Virtual International Stroke Trials Archive (VISTA). Abstract presented at the International Stroke Conference San Francisco, USA. 2007.
    8. Gray LJ, Ali M, Bath PMW, for the VISTA Collaboration. Interconversion of National Institutes of Health Stroke Scale (NIHSS) and Scandinavian Stroke Scale (SSS) impairment/severity measures in stroke trials. Abstract presented at the European Stroke Conference, Glasgow, UK, 2007.
    9. Saini M, Shuaib A, on behalf of the VISTA Investigators. Is hyperthermia is a poor prognostic factor in acute ischemic stroke patients? Abstract for ISC, San Diego, USA, 2009 
    10. Dowlatshahi D, Demchuk AM, Flaherty ML, Ali M, Lyden P and Smith EE, and the VISTA Collaborators. A Clinically Relevant Definition for Hematoma Growth Following Intracerebral Hemorrhage. Abstract Presented at CFNS, Nova Scotia, 2009.
    11. Dowlatshahi D, Smith EE, Flaherty ML, Ali M, Lyden P and Demchuk AM, and the VISTA Collaborators. Small intracerebral hemorrhages are associated with a low rate of hematoma expansion and do not seem appropriate for ICH hemostatic treatment trials. Abstract Presented at CFNS, Nova Scotia, 2009. 
    12. Mishra NK, Diener HC, Lees KR, for the VISTA Collaborations. Thrombolysis is associated with improved outcome in elderly stroke patients: a non-randomized comparison of outcomes amongst patients from the Virtual International Stroke Trials Archive (VISTA). Abstract Presented at ISC 2010, San Antonio, 2009
    13. Tu H, Collins M, Kalman JM, Lees KR, Lyden PD, Donnan GA, Davis SM, on behalf of the VISTA Collaboration. Atrial fibrillation is associated with increased early cardiac morbidity and mortality following ischaemic stroke. Abstract, ESC 2010, Barcelona, Spain
    14. Tu HTH, Collins M, Kalman JM, Lees KR, Lyden PL, Donnan GA, Davis SM, on behalf of the Virtual International Stroke Trials Archive (VISTA) Collaborators. Atrial fibrillation is associated with increased early serious cardiac adverse events following ischemic stroke, Abstract, SSA Annual Scientific Meeting 2010.
    15. Mishra NK, Ahmed N, Kaste M, Wahlgren N, Lees KR for the SITS and VISTA collaborators. Improved outcomes after thrombolysis amongst very elderly: a controlled comparison of the SITS international registry (SITS-ISTR) versus Virtual International Stroke Trials Archive (VISTA) Abstract, ESC 2010, Barcelona, Spain.
    16. Ahmed N, Mishra NK, Hacke W, Lees KR, Wahlgren N, for the SITS-VISTA collaboration Improved outcomes after thrombolysis across baseline NIHSS scores 5-24: controlled comparison of the SITS international registry (SITS-ISTR) versus Virtual International Stroke Trials Archive (VISTA), Abstract, ESC 2010, Barcelona, Spain.
    17. Mishra NK, Ahmed N, Davalos A, Wahlgren N, Lees KR for the SITS- and VISTA collaborators Post thrombolysis outcomes amongst patients with prior stroke and diabetes: controlled comparison of SITS international registry (SITS-ISTR) versus Virtual International Stroke Trials Archive (VISTA), Abstract, ESC 2010, Barcelona, Spain.
    18. Mishra NK, Lyden P, Grotta JC, Lees KR for the VISTA collaborators, Thrombolysis is associated with consistent functional improvement across baseline NIHSS range 5-24: a comparison of outcomes in patients from the Virtual International Stroke Trials Archive (VISTA), Abstract, ESC 2010, Barcelona, Spain. 
    19. Mishra NK, Davis SM, Kaste M, Lees KR for the VISTA collaborators, Comparison of outcomes following thrombolytic therapy amongst patients with prior stroke and diabetes in the Virtual International Stroke Trials Archive (VISTA), Abstract, ESC 2010, Barcelona, Spain.
    20. Mishra NK, Lees KR, Wahlgren NG, Ahmed N, Anderson G, Davalos A, Davis S, Herrero JE, Iversen HK, Kaste M, Lindsberg P, Soinne L, for VISTA and SITS collaborators. Outcomes After Thrombolysis Amongst Patients Aged >=80 Years and Patients Having Diabetes or Previous Stroke: A Synopsis, Presented at ESC, Barcelona, 2010.
    21. Mishra NM, Lees KR, Wahlgren NG, Ahmed N, Anderson G, Bluhmki E, Davalos A, Davis S, Diener HC, Grotta J, Egido J, Klingenberg H, Kaste M, Kobayashi A, Käll TB, Lindsberg P, Lyden P, Ringleb P, Soinne L, for VISTA and SITS collaborators. Treatment effect of thrombolysis in the elderly, in diabetics with prior stroke and across a range of initial severity: results from the Virtual International Stroke Trials Archive (VISTA) and Safe Implementation of Treatment in Stroke-International Stroke Thrombolysis Register (SITS-ISTR). Presentation at the UKSF 2010.
    22. Lees JS, Mishra NK, Saini M, Lyden P, Shuaib A on behalf of the VISTA Collaboration. Low body temperature does not significantly compromise therapeutic effect of alteplase. Poster at ISC, Los Angeles, 2011
    23. Favilla CG, Mullen MT, Ali M, Higgins P, Kasner SE, On behalf of the VISTA Collaboration. Sulfonylurea Use Prior to Stroke Does Not Influence Stroke Severity or Long-term Functional Outcome. ISC, Los Angeles, 2011.
    24. Fulton R, Lees KR, Bluhmki E, Biegert G, Albers G, Davis S, Donnan G, Grotta J, Hacke W, Kaste M, Kummer RV, Shuaib A, Senn S, Toni D, on behalf of the VISTA Collaboration and ECASS, ATLANTIS and EPITHET, Selection for Delayed Intravenous Alteplase Treatment Based on Prognostic Score. Presented at ISC, Los Angeles, 2011.
    25. Fulton R, Gertner J, Lyden P, Lees KR, for the VISTA Collaborators, Effect on study sample size of extending time window for initiation of therapy in acute stroke: an exploratory analysis on the Virtual International Stroke Trials Archive (VISTA) Platform Presentation ESC, Hamburg, Germany 2011.
    26. Kerr DM, Fulton R, Higgins P, Shuaib A, Lyden P, Bath PMW, Lees KR, for the VISTA Collaborators, Response of Blood Pressure and Blood Glucose to Reperfusion in Acute Ischaemic Stroke: evidence from the Virtual International Stroke Trials Archive (VISTA), Platform Presentation ESC, Hamburg, Germany 2011.
    27. Ali M, Bath P, Brady M, Davis S, Diener HC, Donnan G, Fisher M, Hacke W, Hanley DF, Luby M, Tsivgoulis G, Wahlgren NG, Warach S, Lees KR on behalf of the VISTA Steering Committees. Development, Expansion and Use of a Stroke Clinical Trials Resource for Novel Exploratory Analyses, Poster Presentation ESC, Hamburg, Germany 2011.
    28. Ankolekar S, Hogg C, Sprigg N, Bath PMW, for the VISTA collaborators. Relationship between cognitive impairment after stroke and baseline factors and functional outcome: assessment using data from the Virtual International Stroke Trials Archive (VISTA), Poster Presentation ESC, Hamburg, Germany 2011.
    29. Ali M, Hazelton C, Brady M, Lyden P, Pollock A, On Behalf of the VISTA Collaboration. Recovery from Post-Stroke Visual Impairment: Evidence from a Clinical Trials Resource. Presented at UKSF, 2011.
    30. Ali M, Hazelton C, Brady M, Lyden P, Pollock A, On Behalf of the VISTA Collaboration. Recovery from Post-Stroke Visual Impairment: Evidence from a Clinical Trials Resource. Presented at International Stroke Conference 2012, New Orleans, USA.
    31. Kerr DM, Fulton RF, Lees KR, for the VISTA Collaborators. Day 7 NIHSS is a Sensitive Outcome Measure for Exploratory Clinical Trials in Acute Stroke: Evidence from the Virtual International Stroke Trials Archive (VISTA). Presented at International Stroke Conference 2012, New Orleans, USA. 
    32. Rachael L Fulton RL, Kerr DM, Bluhmki E, Lees KR for the VISTA Collaborators and the ECASS, ATLANTIS, EPITHET and NINDS investigators. Validation of Day 7 NIHSS as a Sensitive Outcome Measure for Exploratory Clinical Trials in Acute Stroke: Evidence from pooled randomised control trials in thrombolysis. Platform Presentation at European Stroke Conference 2012, Lisbon, Portugal.
    33. Saini M, Saqqur M, Shuaib A, on behalf of the VISTA Collaboration. Effect of Body-Mass Index and Metabolic syndrome on Ischemic Stroke Outcome, Poster Presentation at European Stroke Conference 2012, Lisbon, Portugal.
    34. Frank B, Fulton R, Weimar C, Shuaib A, Lees KR, for the VISTA Collaborators, Impact of Atrial Fibrillation on Outcome in Thrombolysed Stroke Patients: Evidence from the Virtual International Stroke Trials Archive (VISTA), Platform Presentation at the European Stroke Conference 2012, Lisbon, Portugal.
    35. Goldie FC, Fulton R, Frank B, Lees KR, for the VISTA Collaborators. Interdependence of Stroke Outcome Scales: availability of reliable estimates from the Virtual International Stroke Trials Archive (VISTA), Poster Presented at European Stroke Conference 2012, Lisbon Portugal.
    36. Hajjar K, Diener HC and Lees KR, on behalf of the VISTA Collaboration. Cognitive measures as an adjunct to modified Rankin scale for outcome assessment after acute stroke, Poster Presentation at the European Stroke Conference 2012, Lisbon, Portugal.
    37. Ali M, Bath P, Lyden P, Brady M on behalf of the VISTA Collaboration, Inclusion and Attrition of Patients with Aphasia in Acute Stroke Clinical Trials, Poster Presented at European Stroke Conference 2012, Lisbon, Portugal. 
    38. Ali M, Hazelton C, Lyden P, Pollock, Brady M on behalf of the VISTA Collaboration. Recovery from Post-Stroke Visual Impairment: Evidence from the Virtual International Stroke Trials Archive (VISTA), Platform Presentation at European Stroke Conference 2012, Lisbon, Portugal.
    39. Ali M, Lyden P, Brady M, on behalf of the VISTA Collaboration. Evolution of Post-Stroke Aphasia and Dysarthria in Acute Stroke: Analysis of Data from the Virtual International Stroke Trials Archive (VISTA), Platform Presentation at European Stroke Conference 2012, Lisbon, Portugal.
    40. Tu HTH, Cambbell BCV, Meretoja A, Churilov L, Lees KR, Donnan GA, Davis SM on behalf of the VISTA Investigators, The Impact of CHADS2 Score and Atrial Fibrillation on Early Stroke Morbidity and Mortality, Poster Presented at European Stroke Conference 2012, Lisbon, Portugal.
    41. Ali M, Bath PM, Lyden P, and Brady M, On Behalf of the VISTA Collaboration. Inclusion and Retention of Patients with Aphasia in Acute Stroke Clinical Trials. Poster presented at EFNS 2012, Stockholm, Sweden. 
    42. Ali M, Lyden P, and Brady M, On Behalf of the VISTA Collaboration. Evolution of Aphasia in Acute Stroke, Platform Presentation at EFNS 2012, Stockholm, Sweden. 
    43. Ali M, Brady M, Diener HC, Hanley DF, Wahlgren NG, Warach S, Lees KR, on behalf of the VISTA Steering Committees. The VISTA Collaboration: Exploratory Analysis of Trial Data to Inform RCT Design. Poster presented at EFNS 2012, Stockholm, Sweden.
    44. Ali M, Bath PM, Lyden P, and Brady M, On Behalf of the VISTA Collaboration. Inclusion of Patients with Aphasia in Acute Stroke Clinical Trials: Geographical and Longitudinal Variations. Poster Presentation at UKSF 2012. Harrogate, UK.
    45. Frank B, Grotta JC, Alexandrov AV, Bluhmki E, Lyden P, Meretoja A, Mishra NK, Shuaib A, Wahlgren NG, Weimar C, Lees KR on behalf of the VISTA Collaboration. Do Stroke Patients benefit from Thrombolysis despite Contraindications or Warnings? Presented at ISC 2013, Honolulu, Hawaii, USA.
    46. Frank B, Fulton RL, Goldie FC; Hacke W, Weimar C Lees KR, on behalf of the VISTA Collaboration. Intracluster Correlation Coefficients and Reliability of Randomised Multicentre Stroke Trials within VISTA. Presented at ISC 2013, Honolulu, Hawaii, USA.
    47. Frank B, Fulton RL, Lees KR on behalf of the VISTA Collaboration. The effect of time to treatment on outcome in very elderly thrombolysed stroke patients. Presented at ISC 2013, Honolulu, Hawaii, USA.
    48. Mishra NM, Albers G, Lees KR, on behalf of the VISTA Collaboration, Stroke Severity Threshold For Acute Stroke Trials. Presented at ISC 2013, Honolulu, Hawaii, USA.
    49. Ovbiagele B, Reeves M, Johnston SC, Bath P, Saposnik G, on behalf of the VISTA Collaboration. Intravenous Thrombolysis is Associated with Lower Risk of Severe Disability and Death among SPAN-100 Positive Acute Ischemic Stroke Patients. Presented at ISC 2013, Honolulu, Hawaii, USA. 
    50. Goldie FC, Fulton RL, Dawson J, Lees KR on behalf of the VISTA Collaboration. Exploration of time-course combinations of outcome scales for use in a global test of stroke recovery. . Presented at ISC 2013, Honolulu, Hawaii, USA.
    51. Lees JS, Graham C, Turner AN, on behalf of the VISTA Collaboration. Chronic kidney disease does not influence outcome after acute stroke. Presented at ISC 2013, Honolulu, Hawaii, USA. 
    52. Saposnik G, Johnston SC, Reeves M, Bath P, Ovbiagele B, for the VISTA Collaboration and the Stroke Outcomes Research Canada (SORCan) Working Group. The iScore Predicts Clinical response to Thrombolysis: Results from VISTA collaboration. Presented at ISC 2013, Honolulu, Hawaii, USA. 
    53. Ali M, Fulton R, Quinn T, Brady M, on behalf of the VISTA Collaboration. How well do Trial Outcome Measures Reflect Patients’ Quality of Life (QoL)? A Retrospective Analysis of Clinical Trial Data. Poster presented at ESC 2013, London UK. 
    54. Mazlan-Kepli W, Fulton RF, Walters M, Ali M, Bath P, Dawson J for the VISTA Collaborators. Anti-platelet therapy following ischemic stroke – Continue or change pre-existing therapy? Platform Presentation at ISC, San Diego, USA, 2014. 
    55. Azmil H. Abdul-Rahim, Rachael L. Fulton, Benedikt Frank, Turgut Tatlisumak, Maurizio Paciaroni, Valeria Caso MD, Hans-Christoph Diener, Kennedy R. Lees. The Use of Antithrombotic Therapy in Recent Ischemic Stroke Patients with Atrial Fibrillation: Analysis from VISTA, Presentation at Scottish Heart and Arterial Disease Risk Prevention (SHARP) Annual Scientific Meeting, 21st -22nd November 2013, Dundee, UK. 
    56. Phan T, Chen J, Bearre R, on Behalf of the VISTA Collaboration. Googling stroke ASPECTS to determine disability: Exploratory analysis from VISTA archives, Platform Presentation at ESC 2014, Nice, France.
    57. Al Sheikh S, Fulton RL, Walters M, Shuaib A, Bath P, Dawson J on behalf of the VISTA Collaboration, Adherence to secondary prevention medication early after acute stroke E-Poster Presentation at ESC 2014, Nice, France. 
    58. Abdul-Rahim AH, Fulton RL, Frank B, McMurray JJV, Lees KR, For the VISTA collaborators Associations of Chronic Heart Failure on Outcome in Thrombolyzed Patients with Acute Ischemic Stroke: Analysis from VISTA, Platform Presentation at ESC 2014, Nice, France. 
    59. Ali M, Fulton R, Bath PMW, and Brady M, On Behalf of the VISTA Collaboration Impairment Based Determinants of Quality of Life after Stroke, E-Poster Presentation at ESC 2014, Nice, France.
    60. Mazlan-Kepli W, Fulton RL, Walters M, Ali M, Bath P, Dawson J, for the VISTA Collaborators. Very early initiation of antiplatelet therapy following ischemic stroke is associated with lower recurrence rate. E-Poster Presentation at ESC 2014, Nice, France. 
    61. Al AlShaikh S, Dawson J, Walters M, Bath PM, Shuaib A, on behalf of the VISTA Collaboration, Predictors of non-persistence to stroke secondary prevention medications, Presentation at World Stroke Congress, Istanbul, Turkey, 2014. 
    62. Mazlan-Kepli W, Fulton RF, Walters M, Ali M, Bath P, Dawson J for the VISTA Collaborators. Anti-platelet therapy following ischemic stroke – Continue or change pre-existing therapy? Presentation at Scientific Sessions, Chicago, USA, 2014. 
    63. Hesse K, Fulton RL, Abdul-Rahim AH, Lees KR on behalf of the VISTA Collaboration, Characteristic Adverse Events and their Incidence among Patients Participating in Acute Ischemic Stroke Trials, Poster Presented at World Stroke Congress, Istanbul, Turkey, 2014.
    64. Al AlShaikh S, Dawson J, Fulton R, Walters M, Bath P, Shuaib A on behalf of the VISTA Collaboration, Continuation of secondary prevention medication early after acute stroke. SHARP Conference November, 2014.
    65. Fulton R, Ali M, English C, Rodgers H, Lees KR, Quinn TJ on behalf of the VISTA Collaboration. Describing Clinimetric Properties of the Stroke Impact Scale; Poster Presented at ISC, Nashville, USA 2015.
    66. Fulton R, Ali M, English C, Rodgers H, Lees KR, Quinn TJ on behalf of the VISTA Collaboration. Development and Validation of a short form for the Stroke Impact Scale (SF-SIS). Poster Presented at ISC, Nashville, USA 2015.
    67. Ali M, Brady M, Diener HC, Hanley DF, Wahlgren N, Warach S, Hacke W, Lees KR on behalf of the VISTA Steering Committees. “The VISTA Collaboration: Exploratory Analysis of Trial Data to Inform RCT Design,” Poster Presented at NRS Ageing Specialty Group Conference 2015, Glasgow, UK.
    68. Mazlan-Kepli W, Fulton RL, Walters M, Ali M, Bath P, Dawson J, for the VISTA Collaborators. Very early initiation of antiplatelet therapy following ischemic stroke is associated with lower recurrence rate. Poster Presented at The Royal Medico-Chirurgical Society of Glasgow Annual Research Meeting, Glasgow, UK, March 2015.
    69. Hesse K, Abdul-Rahim AH, Fulton R, Lees KR, for the VISTA collaborators, Ischaemic Stroke Score Calculator: An Online Tool To Improve Stratification Of Adverse Events In Clinical Trials, Poster Presented at European Stroke Organisation Conference, UK April 2015.
    70. Ali M, Fulton R, Quinn T, Bath PM, Veenstra DL, Xu Y, BradyM,on behalf of the VISTA Collaboration, Quality of Life after Acute Ischemic Stroke: Analysis of Utility Data from the Virtual International Stroke Trials Archive (VISTA) Poster Presented at European Stroke Organisation Conference, UK April 2015.
    71. Sykora M, Siarnik P, Diedler J, and for the VISTA Acute Collaborators, Beta-blockers, pneumonia and outcome after ischemic stroke: Evidence from VISTA, Poster Presented at European Stroke Organisation Conference, UK April 2015.
    72. Hametner C, Fulton RL, Kellert L, Abdul-Rahim AH, Ringleb P, Lees KR; on behalf of the VISTA Collaboration, On sex differences in response to intravenous thrombolysis: Evidence from the Virtual International Stroke Trials Archive (VISTA), Poster Presented at European Stroke Organisation Conference, UK April 2015.
    73. Hametner C, Fulton RL, Kellert L, Abdul-Rahim AH, Ringleb P, Lees KR; on behalf of the VISTA Collaboration, Sex-by-hemisphere interaction influences functional outcome: Hypothesis validation using data from the Virtual International Stroke Trials Archive (VISTA), Poster Presented at European Stroke Organisation Conference, UK April 2015.
    74. Hussein H, Niemann N,Stuck L, Qureshi A, on behalf of the VISTA Collaboration, Effect of Cigarette Smoking on Outcomes of Acute Ischemic Stroke Treated with Intravenous or Intra-arterial Thrombolysis: Is There Any Paradox in The Brain? Poster Presentation at AAN Conference, Washington, USA, April 2015.
    75. MacIsaac RL, Ali M, Lees KR, Quinn TJ on behalf of the VISTA Collaborators. Assessing short form versions of the Barthel Index in stroke. Poster Presentation at the ESOC, Barcelona, Spain, 2016 
    76. Scheitz JF, MacIsaac R, Abdul-Rahim AH, Siegerink B, Bath PM, Endres M, Lees KR, Nolte CH, on behalf of the VISTA Collaboration, early initiation of statin treatment and outcome after acute ischaemic stroke. Platform Presentation at ESOC, Barcelona, Spain, 2016 
    77. Singh S, Myint P, Quinn TJ on behalf of the VISTA Collaboration, Comparing and validating long-term stroke prognosis scales, Presented at UKSF 2016, Liverpool, UK

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